Xuhong QIAN 
 

 

Xuhong QIAN    Ph.D., FRSC
Professor of Chemistry
Member, Advisory Commission for Chemistry, NSFC
Fellow of Royal Society of Chemistry, UK
Ambassador Scientist, Alexander von Humboldt Foundation, Germany
 
He was born in Baoying city, Jiangsu province in 1962.
3/2009-, Fellow, The Royal Society of Chemistry, UK.
5/2008, Member, Advisory Commission for Chemistry, National Science Foundation of China
5/2008-, Ambassador Scientist, Alexander von Humboldt Foundation, Germany.
3/2007-12/2008, President, Asian Pacific Confederation of Chemical Engineering.
2007-, Vice President, Chemical Industry and Engineering Society of China
7/2004-, President, East China University of Science and Technology (ECUST), Shanghai.
2007-, Member of Editorial Board, Journal of Fluorine Chemistry, Elsevier.
2005-, Member of Editorial Board, Pesticide Biochemistry and Physiology, Elsevier
2003-2008, Scientist-in-Chief, National Basic Research Key Project (973), The Ministry of Science and Technology.
2002-, Member, Chemical Technology Section of National Academic Degree Council.
9/2000-6/2004.  CheungKong Chair Professor, in Dalian University of Technology.
2000 Research Grant for Outstanding Young Scientist, National Natural Science Foundation of China.
4/1996-10/2000. Vice President, ECUST, Shanghai.
1999. Distinguished 10 Persons in Science and Technology of Shanghai.
9/1995-3/1996. Assistant President, ECUST, Shanghai. 8/1994-9/2000. Professor; 8/1992-7/1994. Associate Professor; 8/1988-8/1992. Lecturer, East China University of Science and Technology (ECUST), Shanghai.
9/1990-1/1992. Alexander von Humboldt Postdoctoral Fellow, Wuerzburg University, West Germany.
8/1989-8/1990. Research Associate, Lamar University, Texas, USA.
6/1988. Ph. D.; 4/1985. Master.; 7/1982. Bachelor, East China Institute of Chemical Technology, Shanghai (Presently, East China University of Science and Technology).
 
1.    Bioorganic Chemistry of Dyes

 

 

Prof. Qian’s research in bioorganic chemistry of dye is about fluorescent sensors and antitumor agents, includes the following aspects:

Fluorescent sensors: Molecular sensor with highly-selectivity for mercuric, cupric, zinc, silver cations, and some anions, derived from naphthalene, naphthalimide, coumarin, BODIPY, and polymer. In addition, fluorescent probe and fluorescent label were also involved in his research.

Antitumor agents: Thio- or Thieno-compounds, Antitumor agents, apoptosis-inducing agents for Bcl-2 protein, topoisomerase inhibitor and photodynamic therapy agent, which were derived from sulfur- or thia- aromatic heterocycle, carboxamide, naphthalimide, benzo[c,d]indol-2-one, phenazine, acridine, acenaphthalenequinone, amino-acenaphtho[1,2-b]pyrrol-carbonitrile and phthalocyanine

 

CHEM. COMMUN. -2008-6339: Highly Sensitive and Selective Pd2+ Sensor of Naphthalimide Derivative Based on Complexation with Alkynes and Thio-heterocycle

CHEM. COMMUN. -2008-4141: Multiple Molecular Logic Functions and Molecular Calculation Facilitated by Surfactant with its Versatility

CHEM. COMMUN. -2008-777: Bulky 4-tritylphenylethynyl substituted boradiazaindacene: Pure red emission, relatively large Stokes shift and inhibition of self-quenching 

CHEM. COMMUN. -2008-1780: A Design Concept of Long Wavelength Fluorescent Analogs of Rhodamine Dyes: Replacement of Oxygen with Silicon Atom

CHEM. COMMUN. -2006-109: Two regioisomeric and exclusively selective Hg(II) sensor molecules composed of a naphthalimide fluorophore and an o-phenylenediamine derived triamide receptor  

CHEM. COMMUN. -2005-239: A new class of long-wavelength fluorophores: strong red fluorescence, convenient synthesis and easy derivation  

CHEM. COMMUN. -2001-2656: Intramolecular aromatic 1,5-hydrogen transfer in preparation of oxacyclic naphthalic anhydride via unusual Pschorr cyclisation

NEW J. CHEM. -2008-472: Chromogenic and fluorescent chemodosimeter for fluoride ion based on

novel anion-catalyzed intramolecular hydrogen transfer

NEW J. CHEM. -2003-337: A polyamidoamine dendrimer with peripheral 1,8-naphthalimide groups capable of acting as a PET fluorescent sensor for metal cations

NEW J. CHEM. -2002-920: Novel heterogeneous PET fluorescent sensors selective for transition metal ions or protons: polymers regularly labelled with naphthalimide

 

J. AM. CHEM. SOC. -2008-16160: A highly sensitive and selective OFF-ON fluorescent sensor for cadmium in aqueous solution and living cell

J. AM. CHEM. SOC. -2004-2272: A highly selective and sensitive fluorescent chemosensor for Hg2+ in neutral buffer aqueous solution  

ANGEW. CHEM. INTl. ED. -2008-8025: A Ratiometric Fluorescent Probe Based on FRET for Imaging Hg2+ in Living Cells

CHEM. EUR. J. -2009-319: Selective and Sensitive Chromo- and Fluorogenic Dual Detection of Anionic Surfactants in Water Based on a Pair of On-Off-On Fluorescent Sensors

CHEM. EUR. J. -2007-7543: Micelle-Induced Versatile Performance of Amphiphilic Intramolecular

Charge-Transfer Fluorescent Molecular Sensors

CHEMPHYSCHEM -2008-1891: Molecular Logic Operations Based on Surfactant Nano-aggregates: Premicelle, Micelle and Its Formation Induced by Inorganic Salt

 

ORG. LETT.  -2008-29: Highly Efficient Energy Transfer in the Light Harvesting System Composed of Three Kinds of Boron-Dipyrromethene Derivatives

ORG. LETT. -2008-633: Isomeric Boron-Fluorine Complexes with Donor-Acceptor Architecture: Strong Solid/Liquid Fluorescence and Large Stokes Shift

ORG. LETT. -2008-633: 2,3,6,7-Tetraamino-9,9-bis(2-ethyl- hexyl)fluorene: new multifunctional monomer for soluble ladder-type conjugated molecules and polymers

ORG. LETT.-2006-3721: A series of polyamide receptor based PET fluorescent sensor molecules: Positively cooperative Hg2+ ion binding with high sensitivity 

ORG. LETT. -2005-3029: Colorimetric and ratiometric fluorescent chemosensor with a large red-shift in emission: Cu(II)-only sensing by deprotonation of secondary amines as receptor conjugated to naphthalimide fluorophore

ORG. LETT. -2005-889: Ratiometric and selective fluorescent sensor for Cu-II based on internal charge transfer (ICT) 

ORG. LETT. -2004-2757: Novel fluorescent pH sensors based on intramolecular hydrogen bonding ability of naphthalimide  

J. ORG. CHEM.  -2008-1571: Novel Fluorescent Fluorine-Boron Complexes: Synthesis, Crystal Structure, Photoluminescence, and Electrochemistry Properties

J. ORG. CHEM. -2006-4308: Detecting Hg2+ ions with an ICT fluorescent sensor molecule: Remarkable emission spectra shift and unique selectivity 

J. ORG. CHEM. -2007-3554: Ratiometric and highly selective fluorescent sensor for cadmium under physiological pH range: A new strategy to discriminate cadmium from zinc

 

KIDNEY INTERNATIONAL -2004-2279: Fluorescent imaging of acute mercuric chloride exposure on cultured human kidney tubular epithelial cells 

CHEM. RES. TOXIC. -2005-1814: Visible study of mercuric ion and its conjugate in living cells of mammals and plants 

CHEMBIOCHEM -2007-113: Novel Bcl-2 inhibitors: Discovery and mechanism study of small organic apoptosis-inducing agents 

J. MATER. CHEM. -2005-2836: A pH-resistant Zn(II) sensor derived from 4-aminonaphthalimide: design, synthesis and intracellular applications

 

MOL. CANCER THER. -2007-484: R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II  

 

BIOORG. MED. CHEM. LETT. -2006-1562: Synthesis and evaluation of novel 8-oxo-8H-cyclopenta[a]acenaphthylene-7-carbonitriles as long-wavelength fluorescent markers for hypoxic cells in solid tumor 

BIOORG. MED. CHEM. LETT. -2005-5909: Novel synthetic isoquinolino[5,4-ab]phenazines: Inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities 

BIOORG. MED. CHEM. LETT. -2005-4864: Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: Effects of intercalation, side chains, and substituent groups

BIOORG. MED. CHEM. LETT. -2005-4864: Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains

BIOORG. MED. CHEM. LETT. -2005-1139: Five-member thio-heterocyclic fused naphthalimides with aminoalkyl side chains: intercalation and photocleavage to DNA (SS)

BIOORG. MED. CHEM. LETT. -2003-5427: Novel naphthalimide hydroperoxide photonucleases: The role of thiocyclic-fused area and the difference in spectra, photochemistry and photobiological activity

 

BIOORG. MED. CHEM. -2007-1356: Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: Synthesis and biological evaluation

BIOORG. MED. CHEM. -2006-6962Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: Various DNA binding geometry and interesting antitumor capacity 

BIOORG. MED. CHEM. -2006-4639: Design, synthesis, and antitumor evaluation of novel acenaphtho[1,2-b]pyrrole-carboxylic acid esters with amino chain substitution 

BIOORG. MED. CHEM. -2005-3149: Novel heterocyclic family of phenyl naphthothiazole carboxamides derived from naphthalimides: synthesis, antitumor evaluation, and DNA photocleavage 

BIOORG. MED. CHEM. -2005-1615: Thio-heterocylic naphthalimides with aminoalkyl side chains: novel alternative tools for photodegradation of genomic DNA without impairment on bioactivities of proteins

 

TETRAHEDRON LETT. -2005-6289: A proton sponge-based fluorescent switch

TETRAHEDRON LETT. -2004-3969: A novel chromatism switcher with double receptors selectively for Ag+ in neutral aqueous solution: 4,5-diaminoalkeneamino-N-alkyl-1,8-naphthalimides  

TETRAHEDRON LETT. -2003-2087: Novel highly efficient fluoroionophores with a peri-effect and strong electron-donating receptors: TICT-promoted PET and signaling response to transition metal cations with low background emission

TETRAHEDRON LETT. -2003-795: Promoting effects of the hydroxymethyl group on the fluorescent signaling recognition of anions by thioureas  

TETRAHEDRON LETT. -2002-2991: 4-Amino-1,8-dicyanonaphthalene derivatives as novel fluorophore and fluorescence switches: efficient synthesis and fluorescence enhancement induced by transition metal ions and protons

TETRAHEDRON LETT. -2002-2995: Synthesis and properties of benzothioxanthene dicarboximide hydroperoxide: an efficient 'time-resolved' DNA photocleaver with long-wavelength

TETRAHEDRON LETT. -2001-6175: N-aroyloxynaphthalimides as novel highly efficient DNA photocleavers: substituent effects  

TETRAHEDRON LETT. -2000-7711: Novel and highly efficient DNA photocleavers: hydroperoxides of heterocyclic-fused naphthalimides  

TETRAHEDRON -2005-11895: Novel DNA bis-intercalators of isoquinolino[4,5-bc]acridines: design, synthesis and evaluation of cytotoxic activity

TETRAHEDRON -2005-11264: Versatile acenaphtho[1,2-b]pyrrol-carbonitriles as a new family of heterocycles: diverse Snar(H)H reactions, cytotoxicity and spectral behavior 

TETRAHEDRON -2005-8717: Synthesis, antitumor and DNA photocleaving activities of novel naphthalene carboxamides: effects of different thio-heterocyclic rings and aminoalkyl side chains

TETRAHEDRON -2005-6634: Synthesis of thiazo- or thiadiazo- naphthalene carboxamides via mercuric intermediates and their antitumor and DNA photocleavage activities  

TETRAHEDRON -2006-10117: Exploiting the deprotonation mechanism for the design of ratiometric and colorimetric Zn2+ fluorescent chemosensor with a large red-shift in emission 

DYES PIGMENTS -2002-247: Synthesis and properties of oligonucleotides containing fluorescent ethenodeoxyadeno sine and ethenodeoxycytidine

DYES PIGMENTS -2001-51: Absorption and fluorescence spectral properties of tetra (fluoroalkoxy) metallophthalocyanines 

DYES PIGMENTS -2001-43: Oxazolonaphthalimides and their hydroperoxides: photophysical and photobiological properties 

DYES PIGMENTS -2004-9: Benzothioxanthene dyes as fluorescent label for DNA hybridization: synthesis and application

DYES PIGMENTS -2004-17: Synthesis and peroxidase-staining properties of novel water soluble polyhydroxylalkyl benzidine dyes 

 

J. FLUORINE CHEM. -2002-161: Synthesis and photosensitizing properties of fluoroalkoxyl phthalocyanine metal complexes

J. FLUORINE CHEM. -2000-69: Synthesis of fluorine-containing oxazolonaphthalimide hydroperoxides as DNA photocleavers

 

J. PHOTOCHEM. PHOTOBIO. B -2001-35: Tetra-trifluoroethoxyl zinc phthalocyanine: potential photosensitizer for use in the photodynamic therapy of cancer 

J. PHOTOCHEM. PHOTOBIO. B -2006-221: Isoquino[4,5-bc]acridines: Design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability 

J. CHEM. SOC.-PERKIN TRANSACTIONS 2 -2000-715: Interaction of naphthyl heterocycles with DNA: effects of thiono and thio groups 

CHEM. LETT. -2005-696: Novel naphthalimide fluorescent sensors selective for certain proteins on basis of non-covalent interactions between enzyme and inhibitor 

 

POLYMER -2002-5731: Synthesis and photophysical properties of 1,8-naphthalimide-labelled PAMAM as PET sensors of protons and of transition metal ions

CHINESE J. ANAL. CHEM. -2004-837: Studies on the room temperature phosphorescence of halogen naphthalic anhydrides

CHINESE CHEM. LETT. -2004-118: Anthracylmethyl benzoazacrown ether as selective fluorescence sensors for Zn2+ 

HETEROCYCL. COMMUN. -2003-229: A new class of DNA intercalator and photocleaver: Bis-naphthailimides with bromo and nitro substituents

INT. J. BIO. MACROMOL. -2006-59: Study on the interaction between 4-(2-diethylanuno- ethylamino)-8-oxo-8H- acenaphtho  [1,2-b]pyrrole- 9-carbonitrile and DNA by molecular spectra 

 

2. Bioorganic Chemistry of Pesticides

 

Prof. Qian’s research in bioorganic chemistry of pesticide is mainly on the pesticide leading compouds derived from aromatic heterocycles and fluorinated compounds, includes the following aspects:

 

Pesticide leads: Insect-growthing regulator, insect behaviour inhibitor, chitin synthesis inhibitor, activate the ecdysone receptor, fly regulator, trehalase inhibitors, antifeedant agent, nicotinic receptor, insecticide, herbicide and fungicide.

New heterocycles:  Fluoro- or fluoroalkoxylated- aromatic heterocycles, Thio- or Thieno-compounds, oxadiazole, thiaoxadiazole, pyridazinone, neonicotinoids, dibenzoyl- butylhydrazine, cyclic amidines

 

BIOORG. MED. CHEM. LETT. -2009, in press: 1,3,4-Oxadiazoline derivatives as novel potential inhibitors targeting chitin biosynthesis:Design, synthesis and biological evaluation.

BIOORG. MED. CHEM. LETT. -2008-6513: cis-Nitromethylene neonicotinoids as new nicotinic family: Synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine

BIOORG. MED. CHEM. -2008-7565: 1,3,4-Oxadiazole-3(2H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation, and role of urea moiety

EURO. J. MED. CHEM. -2009, in press: Novel 4H-1,3,4-oxadiazin-5(6H)-ones with hydrophobic and long alkyl chains:Design, synthesis, and bioactive diversity on inhibition of monoamine oxidase,chitin biosynthesis and tumor cell.

TETRAHEDRON -2008-3877: Solvent-Free Ugi Four-Component Condensation: Application to Synthesis of Philanthotoxins-12 Analogues

SYNLETT. -2008-1341: Ytterbium (III) Perfluorooctanoate-catalyzed One-pot Three-component Synthesis of Fully Substituted Pyrazoles under Solvent-free Conditions

SYNLETT. -2008-3058: One-Pot Synthesis of Trifluoromethyl-Containing Pyrazoles via Sequential Yb(PFO)3-Catalyzed Three-Component Reaction and IBX-Mediated Oxidation

 

J. AGRI. FOOD CHEM. -2007-2288: Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification
J. AGRI. FOOD CHEM. -2006-125: Synthesis and herbicidal activity of novel 3-aminocarbonyl-2-oxazolidinethione derivatives containing a substituted pyridine ring

J. AGRI. FOOD CHEM. -2006-8793: Novel, unnatural benzo-1,2,3-thiadiazole-7-carboxylate elicitors of taxoid biosynthesis

J. AGRI. FOOD CHEM. -2005-3120: Syntheses, antifeedant activity, and QSAR analysis of new oxa(thia)diazolyl 3(2H)-pyridazinones

J. AGRI. FOOD CHEM. -2005-3120: Syntheses, Antifeedant Activity, and QSAR Analysis of New Oxa(thia)diazolyl 3(2 H)-Pyridazinones

J. AGRI. FOOD CHEM. -2003-152: Synthesis and Antifeedant Activity of New Oxadiazolyl 3(2H)-Pyridazinones

J. AGRI. FOOD CHEM. -2001-124: Synthesis and Quantitative Structure-Activity Relationships of New 2,5-Disubstituted-1,3,4-oxadiazoles

J. AGRI. FOOD CHEM. -2001-5279: Synthesis and Quantitative Structure-Activity Relationships of Fluorine-Containing 4,4-Dihydroxylmethyl-2-aryl imino- oxazo (thiazo)lidines as Trehalase Inhibitors

J. AGRI. FOOD CHEM. -1999-4415: Quantitative studies on structure-activity relationship of sulfonylurea and benzoylphenylurea type pesticides and their substituents' bioisosterism using synthons' activity contribution

J. AGRI. FOOD CHEM. -1996-1538: Molecular modeling study on the structure-activity relationship of substituted dibenzoyl-1-tert-butylhydrazines and their structural similarity to 20-hydroxyecdysone

 

ACS SYMPOSIUM SERIES -2005(892)-273: Oxadiazole derivatives as novel insect-growth regulators: Synthesis and structure-bioactivity relationship 

 

J. FLUORINE CHEM. -2006-182: Synthesis and herbicidal activities of fluorine-containing 3-pyridylmethyl-2- phenyliminothiazolidine derivatives

J. FLUORINE CHEM. -2005-297: Synthesis and fungicidal activity of fluorine-containing phenylimino-thiazolidines derivatives

J. FLUORINE CHEM. -2005-53: Synthesis and biological activities of hydroxyl-protected fluorine-containing 4,4-dihydroxylmethyl-2-aryl-iminothiazolidines 

J. FLUORINE CHEM. -2004-1159: Synthesis and fungicidal activity of fluorine-containing phenylimino-thiazolidines derivatives  

J. FLUORINE CHEM. -2004-1609: Syntheses, structures and bioactivities of fluorine-containing phenylimino-thia(oxa)zolidine derivatives as agricultural bioregulators

J. FLUORINE CHEM. -2003-163: Synthesis and insecticidal activities of novel 2,5-disubstituted 1,3,4-oxadiazoles 

J. FLUORINE CHEM. -2003-51: Synthesis and insecticidal activity of new substituted N-aryl-N’-benzoylthiourea compounds

J. FLUORINE CHEM. -2002-63: Syntheses and insecticidal activity of new 2-(5-(trifluoromethyl)pyridyloxymethyl) -1,3,4-oxadiazoles]  

J. FLUORINE CHEM. -2000-111: Fluorine containing heterocyclic compounds: synthesis of 6-substituted-2-substituted-aryl-1,2,4-triazolo[5,1-b] 1,3,5- thia- diazin-7-one derivatives

J. FLUORINE CHEM. -2000-173: Syntheses and insecticidal activities of novel 2-fluorophenyl-5-aryl/cyclopropyl-1,3,4-oxadiazoles

J. FLUORINE CHEM. -2001-143: Synthesis and biological activities of fluorine-containing N, N’-diphenylcarbamimidothioates 

 

CHEM. PHYS. LETT. -2003-489: Intramolecular noncovalent force in cyclic amidines: nonbonded interaction between carbon atoms and heteroatoms

PEST. MANAG. SCI. -2003-933: The toxic and anti-feedant activity of 2H-pyridazin-3-one-substituted 1,3,4-oxadiazoles against the armyworm Pseudaletia separata (Walker) and other insects and mite 

CARBOHYDRATE RESEARCH -2001-79: Syntheses and activities as trehalase inhibitors of N-arylglycosylamines derived from fluorinated anilines

CAN. J. CHEM. -2003-272: N'-tert-Butyl-N'-aroyl-N-(alkoxycarbonylmethyl)-N-aroylhydrazines, a novel nonsteroidal ecdysone agonist: syntheses, insecticidal activity, conformational and crystal structure analysis

J. CHEM. RES. -2006- 626: Synthesis and bioactivities of novel neonicotinoids dioxolane compounds 

J. CHEM. RES. -2000-88: The crystal structure of 1-phenyl-3-methyl-5-[2 '-(4 ''-phenylmethoxylphenyl)ethoxyl]pyrazole, a potential insect juvenile hormone mimic

J. CHEM. RES. -1999-66: The crystal structure of N-(5-phenyl-1,3,4-oxadiazol-2-yl)-N '-benzoyl urea, a novel insect-growth regulator

J. CHEM. RES. -1998-478: Crystal structure of 1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea, an inhibitor of chitin synthesis

CHINESE CHEM. LETT.  -2004-7: Novel Analogues of -TerthienylThienyl 134-Thia(oxa)diazoles as Potential Photoactivated InsecticidesSynthesis and Bioactivity

PESTICIDE BIOCHEM. PHYSIOLOGY -2004-42: Photolarvicidal effect of thienyl 1,3,4-thia(oxa)diazoles and their potential DNA photocleavage

ARKIVOC -2003-141: Synthesis and insecticidal activity of 1,2,4-triazole derivatives

CHEM. LETT. -2001-54: A Novel and Practical Amination of 4,5-Dichloropyridazin-3-ones via Reduction with Hydrazine Hydrate

ORG. PREP. PROCEDURE INTL. -2000-571: A facile synthesis of aryl isothiocyanates from arylamines

 

3. Chemical Biotechnology and Bioengineering

 

Prof. Qian’s researches in chemical biotechnology are about artificial nuclease, cell elicitor and biotransformation.

Artificial nucleases: photonuclease, DNA photocleaver, artificial nuclease of hydrolysis, photodegradation, removal of transgenic material during bio-preparation.

Cell elicitors: Synthetic jasmonate, benzothiazoles, taxoid, gingseng, ganoderma, secondary metabolites.

Biotransformation: Plant cell, baker’s yeast, enantioselective reduction, chemoselective reduction, aromatic nitro compound, hydroxylamine, substituted fluorenones, chiral alcohol.

 

CHEM. COMMUN. -2006-865: Baker's yeast-mediated enantioselective reduction of substituted fluorenones  

CHEM. COMMUN. -2005-2338: A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast

CHEM. COMMUN. -2004-2339: A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers’ yeast

 

APPL. MICROBIO. BIOTECH. -2005-98: A novel synthetic fluoro-containing jasmonate derivative acts as a chemical inducing signal for plant secondary metabolism  

APPL. MICROBIO. BIOTECH. -2006-164:  Novel synthetic 2,6-dichloroisonicotinate derivatives as effective elicitors for inducing the biosynthesis of plant secondary metabolites 

APPL. MICROBIO. BIOTECH. -2006-298: Efficient induction of ginsenoside biosynthesis and alteration of ginsenoside heterogeneity in cell cultures of Panax notoginseng by using chemically synthesized 2-hydroxyethyl jasmonate 

 

BIOORG. MED. CHEM. LETT. -2005-1769: Novel 2-aminothiazonaphthalimides as visible light activatable photonucleases: effects of intercalation, heterocyclic-fused area and side chains

BIOORG. MED. CHEM. LETT. -2003-3513: Thiadiazole: A new family of intercalative photonuclease with electron transfer and radical mechanisms  

BIOORG. MED. CHEM. LETT. -2004-2665: Highly-efficient DNA photocleavers with long wavelength absorptions: thio-heterocyclic fused naphthalimides containing aminoalkyl side chains

BIOORG. MED. CHEM. LETT. -2004-2335: N-aroyloxylthioxo-naphthalimides as DNA photocleavers of aroyloxyl oxygen radicals: synthesis, evaluation, and substituents' effect

BIOORG. MED. CHEM. LETT. -2004-4755: Novel fluoro- and hydroxyl-containing jasmonate derivatives as highly efficient elicitors in suspension cultures of Taxus chinensis 

BIOORG. MED. CHEM. LETT. -2006-803: Hydrolysis of plasmid DNA and RNA by amino alkyl naphthalimide as metal-free artificial nuclease 

BIOORG. MED. CHEM. -2006-2935: Novel fluorescent markers for hypoxic cells of naphthalimides with two heterocyclic side chains for bioreductive binding 

BIOORG. MED. CHEM. -2006-23: Eliminating nucleic acids contaminants by hydrogen peroxide-induced free radicals during the preparation of proteins

 

BIOTECH. BIOENG. -2005-516: Highly efficient strategy for enhancing taxoid production by repeated elicitation with a newly synthesized jasmonate in fed- batch cultivation of Taxus chinensis cells 

BIOTECH. BIOENG. -2004-809: Novel chemically synthesized hydroxyl-containing jasmonates as powerful inducing signals for plant secondary metabolism 

BIOTECH. BIOENG. -2004-595: Novel synthetic jasmonates as highly efficient elicitors for taxoid production by suspension cultures of Taxus chinensis

BIOTECH. PROGR. -2006-331: Novel chemically synthesized salicylate derivative as an effective elicitor for inducing the biosynthesis of plant secondary metabolites 

BIOTECH. AND BIOPROCESS ENGI. -2005-162: Efficient elicitation of ginsenoside biosynthesis in cell cultures of Panax notoginseng by using self-chemically-synthesized jasmonates 

 

BIOCHEM. ENGINEERING. J. -2006-23: Eliminating nucleic acids contaminants by hydrogen peroxide-induced free radicals during the preparation of proteins

TETRAHEDRON LETT. -2004-1247: Naphthalimide-thiazoles as novel photonucleases: molecular design, synthesis, and evaluation  

 

 

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