Prof. Qian’s research in bioorganic chemistry of dyeis about fluorescent sensors and antitumor agents, includes the following aspects:

Fluorescent sensors: Molecular sensor with highly-selectivity for mercuric, cupric, zinc, silver cations, and some anions, derived from naphthalene, naphthalimide, coumarin, BODIPY, and polymer. In addition, fluorescent probe and fluorescent label were also involved in his research.

Antitumor agents: Thio- or Thieno-compounds, Antitumor agents, apoptosis-inducing agents for Bcl-2 protein, topoisomerase inhibitor and photodynamic therapy agent, which were derived fromsulfur- or thia- aromatic heterocycle, carboxamide, naphthalimide, benzo[c,d]indol-2-one, phenazine, acridine, acenaphthalenequinone, amino-acenaphtho[1,2-b]pyrrol-carbonitrile and phthalocyanine

 

CHEM. COMMUN. -2008-6339: Highly Sensitive and Selective Pd2+ Sensor of Naphthalimide Derivative Based on Complexation with Alkynes and Thio-heterocycle

CHEM. COMMUN. -2008-4141: Multiple Molecular Logic Functions and Molecular Calculation Facilitated by Surfactant with its Versatility

CHEM. COMMUN. -2008-777: Bulky 4-tritylphenylethynyl substituted boradiazaindacene: Pure red emission, relatively large Stokes shift and inhibition of self-quenching 

CHEM. COMMUN. -2008-1780: A Design Concept of Long Wavelength Fluorescent Analogs of Rhodamine Dyes: Replacement of Oxygen with Silicon Atom

CHEM. COMMUN. -2006-109: Two regioisomeric and exclusively selective Hg(II) sensor molecules composed of a naphthalimide fluorophore and an o-phenylenediamine derived triamide receptor  

CHEM. COMMUN. -2005-239: A new class of long-wavelength fluorophores: strong red fluorescence, convenient synthesis and easy derivation  

CHEM. COMMUN. -2001-2656: Intramolecular aromatic 1,5-hydrogen transfer in preparation of oxacyclic naphthalic anhydride via unusual Pschorr cyclisation

J. AM. CHEM. SOC.-2010-601:Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent SensorJ. AM. CHEM. SOC. -2008-16160: A highly sensitive and selective OFF-ON fluorescent sensor for cadmium in aqueous solution and living cell
 

J. AM. CHEM. SOC. -2004-2272: A highly selective and sensitive fluorescent chemosensor for Hg2+ in neutral buffer aqueous solution  

ANGEW. CHEM. INTl. ED. -2008-8025: A Ratiometric Fluorescent Probe Based on FRET for Imaging Hg2+ in Living Cells

CHEM. EUR. J. -2007-7543: Micelle-Induced Versatile Performance of Amphiphilic Intramolecular Charge-Transfer Fluorescent Molecular Sensors

ORG. LETT. -2008-473: Ratiometric and Water-Soluble Fluorescent Zinc Sensor of Carboxamidoquinoline with an Alkoxyethylamino Chain as Receptor

ORG. LETT.  -2008-29: Highly Efficient Energy Transfer in the Light Harvesting System Composed of Three Kinds of Boron-Dipyrromethene Derivatives

ORG. LETT. -2008-633: Isomeric Boron-Fluorine Complexes with Donor-Acceptor Architecture: Strong Solid/Liquid Fluorescence and Large Stokes Shift

ORG. LETT. -2008-633: 2,3,6,7-Tetraamino-9,9-bis(2-ethyl- hexyl)fluorene: new multifunctional monomer for soluble ladder-type conjugated molecules and polymers

ORG. LETT.-2006-3721: A series of polyamide receptor based PET fluorescent sensor molecules: Positively cooperative Hg2+ ion binding with high sensitivity 

ORG. LETT. -2005-3029: Colorimetric and ratiometric fluorescent chemosensor with a large red-shift in emission: Cu(II)-only sensing by deprotonation of secondary amines as receptor conjugated to naphthalimide fluorophore

ORG. LETT. -2004-2757: Novel fluorescent pH sensors based on intramolecular hydrogen bonding ability of naphthalimide  

J. ORG. CHEM.  -2008-1571: Novel Fluorescent Fluorine-Boron Complexes: Synthesis, Crystal Structure, Photoluminescence, and Electrochemistry Properties

J. ORG. CHEM. -2007-3554: Ratiometric and highly selective fluorescent sensor for cadmium under physiological pH range: A new strategy to discriminate cadmium from zinc

J. ORG. CHEM. -2006-4308: Detecting Hg2+ ions with an ICT fluorescent sensor molecule: Remarkable emission spectra shift and unique selectivity 

 

MOL. CANCER RES.-2010-1619:B1, a Novel Amonafide Analogue, Overcomes the Resistance Conferred by Bcl-2 in Human Promyelocytic Leukemia HL60 Cells 
MOL. CANCER THER. -2007-484: R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II

 

KIDNEY INTERNATIONAL -2004-2279: Fluorescent imaging of acute mercuric chloride exposure on cultured human kidney tubular epithelial cells 

CHEM. RES. TOX.-2009-483:DNA Double Helix Unwinding Triggers Transcription Block-Dependent Apoptosis: A Semiquantitative Probe of the Response of ATM, RNAPII, and p53 to Two DNA IntercalatorsCHEM. RES. TOXIC. -2005-1814: Visible study of mercuric ion and its conjugate in living cells of mammals and plants 
 

CANCER LETTERS-2009-193:M-2-A induces apoptosis and G(2)-M arrest via inhibiting PI3 K/Akt pathway in HL60 cellsEUR. J. MED. CHEM.-2009-4674: Novel naphthalimide derivatives as potential apoptosis-inducing agents: Design, synthesis and biological evaluation
NEOPLASIA-2009-1226: Naphthalimides Induce G(2) Arrest Through the ATM-Activated Chk2-Executed Pathway in HCT116 Cells
 

BIOORG. MED. CHEM. LETT. -2006-1562: Synthesis and evaluation of novel 8-oxo-8H-cyclopenta[a]acenaphthylene-7-carbonitriles as long-wavelength fluorescent markers for hypoxic cells in solid tumor 

BIOORG. MED. CHEM. LETT. -2005-5909: Novel synthetic isoquinolino[5,4-ab]phenazines: Inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities 

BIOORG. MED. CHEM. LETT. -2005-4864: Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: Effects of intercalation, side chains, and substituent groups

BIOORG. MED. CHEM. LETT. -2005-1139: Five-member thio-heterocyclic fused naphthalimides with aminoalkyl side chains: intercalation and photocleavage to DNA (SS)

BIOORG. MED. CHEM.-2009-7615 :  Novel acenaphtho[1,2-b]pyrrole-carboxylic acid family: Synthesis, cytotoxicity, DNA-binding and cell cycle evaluation
BIOORG. MED. CHEM.-2009-592: Novel naphthalimide-amino acid conjugates with flexible leucine moiety as side chain: Design, synthesis and potential antitumor activity

BIOORG. MED. CHEM. -2006-6962：Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: Various DNA binding geometry and interesting antitumor capacity 

BIOORG. MED. CHEM. -2006-4639: Design, synthesis, and antitumor evaluation of novel acenaphtho[1,2-b]pyrrole-carboxylic acid esters with amino chain substitution 

BIOORG. MED. CHEM. -2005-3149: Novel heterocyclic family of phenyl naphthothiazole carboxamides derived from naphthalimides: synthesis, antitumor evaluation, and DNA photocleavage 

INT. J. BIO. MACROMOL. -2006-59: Study on the interaction between 4-(2-diethylanuno- ethylamino)-8-oxo-8H- acenaphtho  [1,2-b]pyrrole- 9-carbonitrile and DNA by molecular spectra 

TETRAHEDRON LETT. -2004-3969: A novel chromatism switcher with double receptors selectively for Ag+ in neutral aqueous solution: 4,5-diaminoalkeneamino-N-alkyl-1,8-naphthalimides  

TETRAHEDRON LETT. -2003-2087: Novel highly efficient fluoroionophores with a peri-effect and strong electron-donating receptors: TICT-promoted PET and signaling response to transition metal cations with low background emission

TETRAHEDRON LETT. -2003-795: Promoting effects of the hydroxymethyl group on the fluorescent signaling recognition of anions by thioureas  

TETRAHEDRON LETT. -2002-2991: 4-Amino-1,8-dicyanonaphthalene derivatives as novel fluorophore and fluorescence switches: efficient synthesis and fluorescence enhancement induced by transition metal ions and protons

TETRAHEDRON LETT. -2002-2995: Synthesis and properties of benzothioxanthene dicarboximide hydroperoxide: an efficient 'time-resolved' DNA photocleaver with long-wavelength

TETRAHEDRON LETT. -2001-6175: N-aroyloxynaphthalimides as novel highly efficient DNA photocleavers: substituent effects  

TETRAHEDRON-2009-8099: Long-wavelength boradiazaindacene derivatives with two-photon absorption activity and strong emission: versatile candidates for biological imaging applicationsTETRAHEDRON -2006-10117: Exploiting the deprotonation mechanism for the design of ratiometric and colorimetric Zn2+ fluorescent chemosensor with a large red-shift in emission 
TETRAHEDRON -2005-11895: Novel DNA bis-intercalators of isoquinolino[4,5-bc]acridines: design, synthesis and evaluation of cytotoxic activity
 

TETRAHEDRON -2005-11264: Versatile acenaphtho[1,2-b]pyrrol-carbonitriles as a new family of heterocycles: diverse Snar(H)H reactions, cytotoxicity and spectral behavior 

TETRAHEDRON -2005-6634: Synthesis of thiazo- or thiadiazo- naphthalene carboxamides via mercuric intermediates and their antitumor and DNA photocleavage activities  

 

DYES PIGMENTS-2009-127: Novel perfluoroalkyl phthalocyanine metal derivatives: Synthesis and photodynamic activitiesDYES PIGMENTS -2004-17: Synthesis and peroxidase-staining properties of novel water soluble polyhydroxylalkyl benzidine dyes 
 

DYES PIGMENTS -2004-9: Benzothioxanthene dyes as fluorescent label for DNA hybridization: synthesis and application

DYES PIGMENTS -2001-51: Absorption and fluorescence spectral properties of tetra (fluoroalkoxy) metallophthalocyanines 

J. FLUORINE CHEM. -2002-161: Synthesis and photosensitizing properties of fluoroalkoxyl phthalocyanine metal complexes

J. PHOTOCHEM. PHOTOBIO. A -2010-86: Solvent effects for fluorescence and absorption of tetra (fluoroalkyl) metallophthalocyanines: Fluorocarbon solvent cage
J. PHOTOCHEM. PHOTOBIO. A -2010-24:Unusual large Stokes shift and solvatochromic fluorophore Synthesis, spectra, and solvent effect of 6-substituted 2,3-naphthalimide
J. PHOTOCHEM. PHOTOBIO. B -2001-35: Tetra-trifluoroethoxyl zinc phthalocyanine: potential photosensitizer for use in the photodynamic therapy of cancer 

J. PHOTOCHEM. PHOTOBIO. A -2009-181:A pair of regio-isomeric compounds acting as molecular logic gates with different functionsJ. PHOTOCHEM. PHOTOBIO. B -2006-221: Isoquino[4,5-bc]acridines: Design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability 
 

 

CHEM. LETT. -2005-696: Novel naphthalimide fluorescent sensors selective for certain proteins on basis of non-covalent interactions between enzyme and inhibitor 

 

ANALY. CHIM. ACTA 2009-227: Trace mercury (II) detection and separation in serum and water samples using a reusable bifunctional fluorescent sensorCHINESE J. ANAL. CHEM. -2004-837: Studies on the room temperature phosphorescence of halogen naphthalic anhydrides
 

J. CHEM. TECH. BIOTECH. -2009-1051:  Fluorous biphase oxidation of ethyl benzene and benzyl alcohol catalyzed by perfluoroalkyl phthalocyanine complexes

 

SCI. CHINA B-CHEM.-2009-771:Highly sensitive and selective ratiometric fluorescent copper sensors: Different binding affinities modulated by three separate side chains of naphthalimide

 

J. MATER. CHEM. -2005-2836: A pH-resistant Zn(II) sensor derived from 4-aminonaphthalimide: design, synthesis and intracellular applications

CHEMPHYSCHEM -2008-1891: Molecular Logic Operations Based on Surfactant Nano-aggregates: Premicelle, Micelle and Its Formation Induced by Inorganic Salt

POLYMER -2002-5731: Synthesis and photophysical properties of 1,8-naphthalimide-labelled PAMAM as PET sensors of protons and of transition metal ions

 

HETEROCYCL. COMMUN. -2003-229: A new class of DNA intercalator and photocleaver: Bis-naphthailimides with bromo and nitro substituents

 

 

Prof. Qian’s research in bioorganic chemistry of pesticide is mainly on the pesticide leading compouds derived from aromatic heterocycles and fluorinated compounds,includes the following aspects:

 

Pesticide leads: Insect-growthing regulator, insect behaviour inhibitor, chitin synthesis inhibitor, activate the ecdysone receptor, fly regulator, trehalase inhibitors, antifeedant agent, nicotinic receptor, insecticide, herbicide and fungicide.

New heterocycles: Fluoro- or fluoroalkoxylated- aromatic heterocycles, Thio- or Thieno-compounds, oxadiazole, thiaoxadiazole, pyridazinone, neonicotinoids, dibenzoyl- butylhydrazine, cyclic amidines

 

BIOORG. MED. CHEM. LETT. -2009-332:1,3,4-Oxadiazoline derivatives as novel potential inhibitors targeting chitin biosynthesis: Design, synthesis and biological evaluationBIOORG. MED. CHEM. LETT. -2008-6513: cis-Nitromethylene neonicotinoids as new nicotinic family: Synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine
 

BIOORG. MED. CHEM. -2008-7565: 1,3,4-Oxadiazole-3(2H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation, and role of urea moiety

EUR. J. MED. CHEM.-2009-2985: Diacylhydrazine derivatives as novel potential chitin biosynthesis inhibitors: Design, synthesis, and structure-activity relationshipNovel 4H-1,3,4-oxadiazin-5(6H)-ones with hydrophobic and long alkyl chains: Design, synthesis, and bioactive diversity on inhibition of monoamine oxidase, chitin biosynthesis and tumor cell
EUR. J. MED. CHEM.-2009-2113:

ORG. BIOMOL. CHEM.-2010-2386:A general strategy for construction of a difluoromethyl compound library and its application in synthesis of pseudopeptides bearing a terminal difluoromethyl group

 

TETRAHEDRON-2009-10377: One step from nitro to oxime: a convenient preparation of unsaturated oximes by the reduction of the corresponding vinylnitro compoundsTETRAHEDRON -2008-3877: Solvent-Free Ugi Four-Component Condensation: Application to Synthesis of Philanthotoxins-12 Analogues
 

SYNLETT. -2008-1341:Ytterbium (III) Perfluorooctanoate-catalyzed One-pot Three-component Synthesis of Fully Substituted Pyrazoles under Solvent-free Conditions

SYNLETT. -2008-3058: One-Pot Synthesis of Trifluoromethyl-Containing Pyrazoles via Sequential Yb(PFO)3-Catalyzed Three-Component Reaction and IBX-Mediated Oxidation

J. AGRI. FOOD CHEM.-2010- 2696:Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure, and Insecticidal ActivitiesChina: Forward to the Green Pesticides via a Basic Research Program
J. AGRI. FOOD CHEM.-2010- 2613:

J. AGRI. FOOD CHEM.-2010- 2736:Synthesis and Insecticidal Activity of Heptafluoroisopropyl-Containing Benzoylphenylurea Structures
J. AGRI. FOOD CHEM. -2009-951: Design, Synthesis, and Insecticidal Activities of Novel Analogues of Neonicotinoids: Replacement of Nitromethylene with Nitroconjugated System

J. AGRI. FOOD CHEM. -2007-2288: Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification
J. AGRI. FOOD CHEM. -2006-125:Synthesis and herbicidal activity of novel 3-aminocarbonyl-2-oxazolidinethione derivatives containing a substituted pyridine ring

J. AGRI. FOOD CHEM. -2006-8793: Novel, unnatural benzo-1,2,3-thiadiazole-7-carboxylate elicitors of taxoid biosynthesis

J. AGRI. FOOD CHEM. -2005-3120:Syntheses, antifeedant activity, and QSAR analysis of new oxa(thia)diazolyl 3(2H)-pyridazinones

J. AGRI. FOOD CHEM. -2003-152: Synthesis and Antifeedant Activity of New Oxadiazolyl 3(2H)-Pyridazinones

J. AGRI. FOOD CHEM. -2001-124: Synthesis and Quantitative Structure-Activity Relationships of New 2,5-Disubstituted-1,3,4-oxadiazoles

J. AGRI. FOOD CHEM. -2001-5279: Synthesis and Quantitative Structure-Activity Relationships of Fluorine-Containing 4,4-Dihydroxylmethyl-2-aryl imino- oxazo (thiazo)lidines as Trehalase Inhibitors

J. AGRI. FOOD CHEM. -1999-4415: Quantitative studies on structure-activity relationship of sulfonylurea and benzoylphenylurea type pesticides and their substituents' bioisosterism using synthons' activity contribution

J. AGRI. FOOD CHEM. -1996-1538: Molecular modeling study on the structure-activity relationship of substituted dibenzoyl-1-tert-butylhydrazines and their structural similarity to 20-hydroxyecdysone

PEST MANAGEMENT SCI.-2010-238: Recent progress of highly efficient in vivo biological screening for novel agrochemicals in China
PESTICIDE BIOCHEM. PHYSIOLOGY -2004-42: Photolarvicidal effect of thienyl 1,3,4-thia(oxa)diazoles and their potential DNA photocleavage

ACS SYMPOSIUM SERIES -2005(892)-273: Oxadiazole derivatives as novel insect-growth regulators: Synthesis and structure-bioactivity relationship 

J. FLUORINE CHEM. -2006-182: Synthesis and herbicidal activities of fluorine-containing 3-pyridylmethyl-2- phenyliminothiazolidine derivatives

J. FLUORINE CHEM. -2005-297: Synthesis and fungicidal activity of fluorine-containing phenylimino-thiazolidines derivatives

J. FLUORINE CHEM. -2005-53: Synthesis and biological activities of hydroxyl-protected fluorine-containing 4,4-dihydroxylmethyl-2-aryl-iminothiazolidines 

J. FLUORINE CHEM. -2004-1159: Synthesis and fungicidal activity of fluorine-containing phenylimino-thiazolidines derivatives  

J. FLUORINE CHEM. -2004-1609: Syntheses, structures and bioactivities of fluorine-containing phenylimino-thia(oxa)zolidine derivatives as agricultural bioregulators

J. FLUORINE CHEM. -2003-163: Synthesis and insecticidal activities of novel 2,5-disubstituted 1,3,4-oxadiazoles 

J. FLUORINE CHEM. -2003-51: Synthesis and insecticidal activity of new substituted N-aryl-N’-benzoylthiourea compounds

J. FLUORINE CHEM. -2002-63: Syntheses and insecticidal activity of new 2-(5-(trifluoromethyl)pyridyloxymethyl) -1,3,4-oxadiazoles]  

J. FLUORINE CHEM. -2000-111: Fluorine containing heterocyclic compounds: synthesis of 6-substituted-2-substituted-aryl-1,2,4-triazolo[5,1-b] 1,3,5- thia- diazin-7-one derivatives

J. FLUORINE CHEM. -2000-173: Syntheses and insecticidal activities of novel 2-fluorophenyl-5-aryl/cyclopropyl-1,3,4-oxadiazoles

J. FLUORINE CHEM. -2001-143: Synthesis and biological activities of fluorine-containing N, N’-diphenylcarbamimidothioates 

 

CHEM. PHYS. LETT. -2003-489: Intramolecular noncovalent force in cyclic amidines: nonbonded interaction between carbon atoms and heteroatoms

PEST. MANAG. SCI. -2003-933: The toxic and anti-feedant activity of 2H-pyridazin-3-one-substituted 1,3,4-oxadiazoles against the armyworm Pseudaletia separata (Walker) and other insects and mite 

CARBOHYDRATE RESEARCH -2001-79: Syntheses and activities as trehalase inhibitors of N-arylglycosylamines derived from fluorinated anilines

CAN. J. CHEM. -2003-272: N'-tert-Butyl-N'-aroyl-N-(alkoxycarbonylmethyl)-N- aroylhydrazines, a novel nonsteroidal ecdysone agonist: syntheses, insecticidal activity, conformational and crystal structure analysis

J. CHEM. RES. -2006- 626: Synthesis and bioactivities of novel neonicotinoids dioxolane compounds 

J. CHEM. RES. -2000-88: The crystal structure of 1-phenyl-3-methyl-5-[2 '-(4 ''-phenylmethoxylphenyl)ethoxyl]pyrazole, a potential insect juvenile hormone mimic

J. CHEM. RES. -1999-66: The crystal structure of N-(5-phenyl-1,3,4-oxadiazol-2-yl)-N '-benzoyl urea, a novel insect-growth regulator

J. CHEM. RES. -1998-478: Crystal structure of 1-(3,5-dichloro-2,4-difluorophenyl)-3- (2,6-difluorobenzoyl)urea, an inhibitor of chitin synthesis

ARKIVOC -2003-141: Synthesis and insecticidal activity of 1,2,4-triazole derivatives

CHINESE CHEM. LETT.  -2004-7: Novel Analogues of -Terthienyl，Thienyl 1，3，4-Thia(oxa)diazoles as Potential Photoactivated Insecticides：Synthesis and Bioactivity

CHEM. LETT. -2001-54: A Novel and Practical Amination of 4,5-Dichloropyridazin-3-ones via Reduction with Hydrazine Hydrate

ORG. PREP. PROCEDURE INTL. -2000-571: A facile synthesis of aryl isothiocyanates from arylamines

 

MOL. DIVERSITY-2010-501: A mild and efficient synthesis of monofluorinated alpha-lactam pseudopeptides via a novel dehydrofluorination of Ugi products

 

SCI. CHINA-CHEM.-2010-1509:An efficient three-component domino synthesis of difluoromethyl-containing 1,4-dihydropyridines under solvent and catalyst free conditions
PHOSPHORUS SULFUR AND SILICON-2009-1825: Novel Heterocyclic Compounds Containing Sulfur: Synthesis and Insecticidal Activity of (2-Chlorothiazol-5-yl)methyl 2-Phenyliminothiazolidines

 

HETEROATOM CHEM.-2009-418: Design, synthesis, and Evaluation of Unsymmetrical Difluoro-Boron Complexes with Imidazoline as Potential Fungicides 
J. COMPUT. CHEM. -2010-586: Novel Dimer Based Descriptors with Solvational Computation for QSAR Study of Oxadiazoylbenzoyl-ureas as Novel Insect-growth Regulators
GREEN CHEM.-2009-1414: A revisit to the Hantzsch reaction: Unexpected products beyond 1,4-dihydropyridines
 

Prof. Qian’s researches in chemical biotechnology are about artificial nuclease, cell elicitor and biotransformation.

Artificial nucleases: photonuclease, DNA photocleaver, artificial nuclease of hydrolysis, photodegradation, removal of transgenic material during bio-preparation.

Cell elicitors:Synthetic jasmonate, benzothiazoles, taxoid, gingseng, ganoderma, secondary metabolites.

Biotransformation: Plant cell, baker’s yeast, enantioselective reduction, chemoselective reduction, aromatic nitro compound, hydroxylamine, substituted fluorenones, chiral alcohol.

CHEM. COMMUN. -2004-2339: A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers’ yeast

TETRAHEDRON-ASYMMETRY-2010-825:Preparation of chiral trans-5-substituted-acenaphthene- 1,2-diols by baker's yeast-mediated reduction of 5-substituted-acenaphthylene-1,2-diones
TETRAHEDRON LETT. -2004-1247: Naphthalimide-thiazoles as novel photonucleases: molecular design, synthesis, and evaluation  

APPL. MICROBIO. BIOTECH. -2006-298:Efficient induction of ginsenoside biosynthesis and alteration of ginsenoside heterogeneity in cell cultures of Panax notoginseng by using chemically synthesized 2-hydroxyethyl jasmonate 

APPL. MICROBIO. BIOTECH. -2006-164: Novel synthetic 2,6-dichloroisonicotinate derivatives as effective elicitors for inducing the biosynthesis of plant secondary metabolites 

APPL. MICROBIO. BIOTECH. -2005-98: A novel synthetic fluoro-containing jasmonate derivative acts as a chemical inducing signal for plant secondary metabolism  

BIOORG. MED. CHEM. LETT. -2003-3513: Thiadiazole: A new family of intercalative photonuclease with electron transfer and radical mechanisms  

BIOORG. MED. CHEM. LETT. -2004-4755:Novel fluoro- and hydroxyl-containing jasmonate derivatives as highly efficient elicitors in suspension cultures of Taxus chinensis 

BIOORG. MED. CHEM. LETT. -2006-803: Hydrolysis of plasmid DNA and RNA by amino alkyl naphthalimide as metal-free artificial nuclease 

BIOORG. MED. CHEM. -2006-2935: Novel fluorescent markers for hypoxic cells of naphthalimides with two heterocyclic side chains for bioreductive binding 

BIOTECH. BIOENG. -2005-516:Highly efficient strategy for enhancing taxoid production by repeated elicitation with a newly synthesized jasmonate in fed- batch cultivation of Taxus chinensis cells 

BIOTECH. BIOENG. -2004-809: Novel chemically synthesized hydroxyl-containing jasmonates as powerful inducing signals for plant secondary metabolism 

BIOTECH. PROGR. -2006-331: Novel chemically synthesized salicylate derivative as an effective elicitor for inducing the biosynthesis of plant secondary metabolites 

BIOTECH. AND BIOPROCESS ENGI. -2005-162: Efficient elicitation of ginsenoside biosynthesis in cell cultures of Panax notoginseng by using self-chemically-synthesized jasmonates 

 

BIOCHEM. ENGINEERING. J. -2006-23: Eliminating nucleic acids contaminants by hydrogen peroxide-induced free radicals during the preparation of proteins