【个人简介】
 施敏:长江学者 教授 
        施敏教授.1963年1月生于上海,研究员，国家 重 点 基 础 研 究项 目 973 的 子 课 题 负 责 人、教育部“长江学者奖励计划”特聘教授。
   
教育 Education:
1980年 9月- 1984年 7月 ,华东理工大学精细化工系,获学士学位 .
1984年 7月- 1985年10月,大连外国语学院出国留学生预备班进修日语 
1985年10月 -1988年 3月 ,日本歧阜大学工业化学系,获硕士学位(有机合成化学 )
1988年 4月 - 1991年3月,日本大阪大学工学部,获博士学位(有机光化学 )

工作经历 Experience:
1991年 4月 -1993年3月,日本歧阜Shellac高分子材料公司开发部 ,技术员 .
1993年 4月 -1995年10月,日本歧阜药科大学药品合成化学研究室,助教(不对称合成化学)
1995年 10月-1996年12月,国俄克拉亥玛大学从事博士后的研究工作 .(金属有机 )
1996年 12月-1998年 3月,日本科学技术振兴事业团 - ERATO,井上光不对称反应课题组从事博士后的研究工作 .(不对称光 化学反应 )
1998年 4 月,进有机所工作.

在国外学习和工作时的主要学术成就
1.发现了一些三苯甲基的衍生物经过光的直接照射, 二个苯基会发生偶联脱离, 并产生一个卡宾中间体的新光化学反应.
2.从糖类化合物出发, 合成了一些新的具有C2-对称性的四氢吡咯环的ß-氨基醇和ß-氨基硫醇 . 在这些催化量的手性配体存在下, 醛类化合物和金属锌试剂加成反应产物的ee 值可以达到99 % .
3.发现了烯丙基锡在金属钯催化下, 可以和CO2发生一个定量型的新的插入反应.这一研究结果对地球大气中的主要温室气体CO2 的固定, 开辟了一崭新的研究方向.
   完成以上三个方面的工作后, 共有39 篇论文得到发表并被SCI 收录. 在SCI 中被他人引用共 有 44 次

【主要教学科研成果】
获奖 Award:
    2000年 国 家 自 然 科 学 基 金 委 杰 出青 年基 金 获 得 者 

【论文发表情况】
发表文章 Publications list (2000-):
1. Titanium(IV) Bromide and Boron(III) Tribromide Promoted Baylis-Hillman Reactions of Arylaldehydes with 3-Butyn-2-one.

Min Shi* and Chun-Jiang Wang, Helv. Chim. Acta, 2002, 85, 841.

2. The Reaction of Amines with Benzyl Halides Under CO2 Atmosphere.

Min Shi* and Yu-Mei Shen, Helv. Chim. Acta, 2001, 84, 3357.

3. C2-Symmetric Dialkoxyphosphoramide and Dialkoxythiophosphoramide Derivatives of (1R, 2R)-1,2-Diaminocyclohexane as Chiral Ligands for the Titanium(IV) Alkoxide-promoted Asymmetric Addition Reactions of Diethylzinc to Arylaldehydes.

Min Shi,* Xiao-Feng Wu, and Guobin Rong, Chirality, 2002, 14, 90.

4. Lewis Base and L-Proline Co-Catalyzed Baylis-Hillman Reaction of Arylaldehydes with Methyl Vinyl Ketone.

Min Shi,* Jian-Kang Jiang, and Chao-Qun Li, Tetrahedron Lett., 2002, 43, 127.

5. The Synthesis of New Chiral Rhodium Complexes and Their Crystal Structures

Min Shi* and Gui-Xin Lei, Applied Organometa. Chem., 2002, 16, 55.

6. Titanium(IV) Chloride, Boron(III) Chloride, Zirconium(IV) Chloride and Amine-Promoted Baylis-Hillman Reaction.

Min Shi,* Jian-Kang Jiang, and Shi-Cong Cui, Molecules, 2001, 6, 852.

7. Transition Metal Catalyzed Reactions of Propargylamine with Carbon Dioxide and Carbon Disulfide.

Min Shi* and Yu-Mei Shen, J. Org. Chem., 2002, 67, 16.

8. Perfluorinated rare earth metals catalyzed nitration of aromatic compounds.

Min Shi* and Shi-Cong Cui, J. Fluor. Chem., 2002, 113, 207.

9. VO(acac)2 Catalyzed Oxidative Coupling Reactions of Phosphonium Salts.

Min Shi* and Bo Xu, J. Org. Chem., 2002, 67, 294.

10. Axially Dissymmetric Binaphthyldiimine Chiral Salen Type Ligands For Copper-Catalyzed Asymmetric Aziridination.
Min Shi,* Chuan-Jiang Wang, and Albert S. C. Chan, Tetrahedron:Asymmetry, 2001, 12, 3105.

11. Boron(III) Tribromide or Titanium(IV) Bromide and Lewis Base Promoted Baylis-Hillman Reaction.

Min Shi* and Shi-Cong Cui, Chinese J. Chem., 2002, 20, 277.

12. Reactions of 5,5-dimethyl-4-methylene-1,3-dioxolan-2-one with amines in the presence of palladium catalyst.

Min Shi,* Yu-Mei Shen, and Ya-Jun Chen, Heterocycles, 2002, 57, 245.

13. Lewis base effects in the Baylis-Hillman reaction of imines with methyl vinyl ketones.

Min Shi* and Yong-Mei Xu, Eur. J. Org. Chem., 2002, 696.

14. The reactions of thiols and diphenyldisulfide with the terminal substituted methylenecyclopropanes.
Bo Xu, Yu Chen† and Min Shi,* Tetrahedron Lett., 2002, 43, 2781.

15. Baylis-Hillman Reaction of Arylaldehydes with Phenyl Vinyl Ketone, Phenyl Acrylate and Phenyl Thioacrylate.

Min Shi,* Chao-Qun Li, and Jian-Kang Jiang, Helv. Chim. Acta, 2002, 85, 1051.

16. Synthesis of a Novel Copper(II) Complex and Its Crystal Structure.
Min Shi,* and Jian-Kang Jiang, J. Organometa. Chem., 2002, 650, 274.

17. Axially Dissymmetric (R)-(+)-5,5’,6,6’,7,7’,8,8’-Octahydro-[1,1’]binaphthyldiimine Chiral Salen Type Ligands For Copper-Catalyzed Asymmetric Aziridination.
Min Shi* and Chun-Jiang Wang, Chirality, 2002, 14, 412.

18. A Novel Reaction of 1,8-Diazabicyclo[5.4.0]undec-7-ene [DBU] or 1,5-Diazabicyclo[4.3.0]non-5-ene [DBN] with Benzyl Halides in the Presence of Water.

Min Shi* and Yu-Mei Shen, Helv. Chim. Acta, 2002, 85, 1355.

19. Electrophilic Aromatic Nitration Using Perfluorinated Rare Earth Metal Salts in Fluorous Phase.

Min Shi* and Shi-Cong Cui, J. Chem. Soc., Chem. Commun., 2002, 994.

20. Baylis-Hillman reactions of N-arylidenediphenylphosphinamides with methyl vinyl ketone, methyl acrylate, and acrylonitrile.
Min Shi* and Gui-Ling Zhao, Tetrahedron Lett., 2002, 43, 4499.

21. Synthesis of Mixed Carbonate via a Three-Components Coupling of Alcohol, CO2, and Alkyl Halide in the Presence of K2CO3 and Tetrabutylammonium Iodide.

Min Shi* and Yu-Mei Shen, Molecules, 2002, 7, 386.

22. The Lewis acids catalyzed ring opening reactions of methylenecyclopropanes with alcoholic or acidic nucleophiles.

Min Shi* and Bo Xu, Org. Lett., 2002, 4, 2145.

23. The diastereoselective Baylis-Hillman reaction of chiral non-racemic N-sulfinimines with cyclopent-2-en-1-one.

Min Shi* and Yong-Mei Xu, Tetrahedron:Asymmetry, 2002, 13, 1195.

24. Friedel-Crafts reaction catalyzed by perfluorinated rare earth metals.

Min Shi*, Shi-Cong Cui, J. Fluor. Chem., 2002, 116, 143.

25. Catalytic asymmetric Baylis-Hillman reaction of imines with methyl vinyl ketone and methyl acrylate.

Min Shi* and Yong-Mei Xu, Angew. Chem. Int. Ed. Engl. 2002, 41, 4503.

26. The First Synthesis and Isolation of V:SHAPETYPE id=_x0000_t75 coordsize=“21600,21600“ o:spt=“75“ o:preferrelative=“t“ path=“m@4@5l@4@11@9@11@9@5xe“ filled=“f“ stroked=“f“>Bis(aryloxy)phosphorothioylsulfenyl Iodides‘ (=Bis(aryloxy)phosphinesulfenyl Iodide P-Sulfides) from the Reaction of S,S’ -(Diphenylstannylene) O,O,O’,O’-Tetraaryl Bis[phosphorodithioates] (=[(Diphenylstannylene)bis(thio)]bis[bis(aryloxy)phosphine P-Sulfides]) with N-Iodosuccinimide.

Min Shi* and Shinji Kato,† Helv. Chim. Acta, 2002, 85, 2559.

27. A Novel Chiral Silver(I) Complex via the Reaction of Thiaxazolidinethione with AgOAc.

Min Shi,* Jian-Kang Jiang and Gui-Ling Zhao, Eur. J. Inorg. Chem., 2002, 3264.

28. Lewis base effects in the Baylis-Hillman reaction of arylaldehydes and N-arylidene-4-methylbenzenesulfonamides with a,b-unsaturated cyclic ketones.

Min Shi,* Yong-Mei Xu, Gui-Ling Zhao and Xiao-Feng Wu, Eur. J. Org. Chem., 2002, 3666.

29. Titanium(IV) Bromide and Boron(III) Tribromide Promoted Reactions of Arylaldehydes with 3-Butyn-2-one, Methyl Propiolate and Propynenitrile.

Min Shi* and Chun-Jiang Wang, Tetrahedron, 2002, 58, 9063.

30. A Novel Ring-Opening Reaction of Methylenecyclopropanes with Aromatic Amines Catalyzed By Lewis Acids.

Min Shi,*a Yu Chen,b Bo Xua and Jie Tang,b Tetrahedron Lett., 2002, 43, 8019.

31. Axially Dissymmetric Chiral (R)-N,N′-Bis(2-hydroxy-3,5-di-tert-butyl-arylmethyl)- 1,1′- binaphthalene-2,2′-diamine as Chiral Ligands in the Reaction of Diethylzinc to aldehydes.

Min Shi,* Wei-Liang Duan,† and Rong, Guo-bin,† Chinese J. Chem., 2002, 20, 1319.

32. An Exploration of Asymmetric Baylis-Hillman Reaction Catalyzed by Quinidine Derived Chiral Amine.

Min Shi* and Jian-Kang Jiang, Tetrahedron:Asymmetry, 2002, 13, 1941.

33. Axially Dissymmetric Binaphthyldiimine Chiral Salen-Type Ligands For Catalytic Asymmetric Addition of Diethylzinc to Aldehyde.

Min Shi* and Chun-Jiang Wang, Tetrahedron:Asymmetry, 2002, 13, 2161.

34. One pot aza-Baylis-Hillman reaction of arylaldehyde, diphenylphosphinamide with methyl vinyl ketone in the presence of TiCl4, PPh3, and Et3N.
Min Shi* and Gui-Ling Zhao, Tetrahedron Lett., 2002, 43, 9171.

35. The Reactions of DMSO with Arylaldehydes in the Presence of Sodium Hydride

Min Shi* and Yu-Mei Shen, J. Chem. Res., 2002, in press.

【研究方向】
研究领域 Research field:
1.新型手性金属络合物和手性配体的合成及其不对称催化反应的研 究,争取能够把催化反应的手性金属络合物分离得到,并能通过X-ray 晶体衍射确定其结构.
2.我们现在正在合成一些新配体用于 Baylis-Hillman 反应中作为手性催化剂,希望对于该反应的手性诱导能有突破.
3.进一步研究利用化学反应固定CO2的方法,研究其反应机理.除了通过有机胺以外,我们还打算结合以前在国外所作的利用金属Pd催化固定 CO2的反应,研究一些利用金属催化剂固定CO2的新反应.
4.我们同日本大阪工学部井上教授的井上Photochirogenesis ERATO Project (JST) 有一个国际合作研究项目, 主要是在利用光和手性增感剂进行手性诱导.