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| 2009-06-16 |
男，1967年生于湖北黄石。1989.7于湖北大学获理学学士学位；1992.7华东化工学院获工学硕士学位，1996.7华东理工大学获工学博士学位。2002.8日本京都大学（Kyoto University）工学部Guest Scholar; 2005.3-9美国宾夕法尼亚大学（University of Pennsylvania）Visiting Professor。 1992.7-1994.10华东理工大学助教; 1994.11-1996.10讲师；1996.11-1999.11副教授；1999.11－至今，教授；2000.5－至今博士生导师。2004.9－2007.10华东理工大学特聘教授；2008.3至今教育部“长江学者计划”特聘教授；2008年12月至今国务院学位办第六届学科评议组成员。 1993.3-1997.5任华东理工大学技物所室主任；1997.6-2001.4先后任华东理工大学技物所副所长，支部书记；华东理工大学生物材料研究所所长；2001.5至今教育部医用生物材料工程研究中心主任; 2003.3至今国家医用生物材料动员中心主任。 1996年入选上海市科技启明星；2000年入选教育部跨世纪优秀人才；2001年上海市优秀科技启明星；2004年获得国家杰出青年科学基金，第二届上海市青年科技英才，霍英东教育基金；2006年入选“新世纪百千万人才工程”国家级人选，获国务院特殊津贴，中国发明创业奖，第二届上海优秀发明人；2007年获上海市十大科技精英，上海市优秀学科带头人，中国青年科技奖，何梁何利科技创新奖。 作为第一完成人，获得2003年度国家科技进步奖二等奖以及2002年国际INPEX医药类创新优秀奖银奖；2001年上海市发明创造专利二等奖；2001年上海市优秀产学研工程项目二等奖；2000年上海市科技进步奖二等奖；1998年世界华人发明博览会金奖等。 主要研究方向 从事生物材料及相关纳米材料的研究，主要包括：生物活性及降解材料、可注射生物材料、药物传输体系和智能生物材料。应用领域主要集中于硬组织修复、皮肤修复、止血和药物/蛋白控释等。 代表性论文 1. Biomaterials，2009－2764：Development of mussel adhesive polypeptide mimic coating for in-situ inducing re-endothelialization of intravascular stent devices通讯作者 2. Biomaterials，2009－2340：Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan通讯作者 3. Biomaterials，2009－1080：Preparation and characterization of bioactive mesoporous wollastonite – Polycaprolactone composite scaffold通讯作者 4. Biomaterials，2009－1715：Enhanced bioactivity of bone morphogenetic protein-2 with low dose of 2-N,6-O-sulfated chitosan in vitro and in vivo通讯作者 5. Biomaterials, 2007－1414：Preparation of hemoglobin-loaded nano-sized particles with porous structure as oxygen carriers通讯作者 6. Biomaterials, 2007－3456：Copolypeptides of 3,4-Dihydroxyphenylalanine and L-lysline to Mimic Marine Adhesive Protein通讯作者 7. Biomaterials, 2006－5003：Rheological Properties of Concentrated Aqueous Injectable Calcium Phosphate Cement Slurry第1作者 8. Biomaterials, 2003-2995:The Exothermal behavior in the Hydration Process of Calcium Phosphate Cement第1作者 9. Biomaterials, 2003-4103:Effects of the Granularity of Raw Materials on the Hydration and Hardening Process of Calcium Phosphate Cement第1作者 10. Biomaterial, 2001-301:Kinetics of Hydroxyapatite Precipitation at pH 10 to 11 第1作者 11. Tissue Engineering, 2006－1097：Evaluation of biocompatibility of artificial blood cells 通讯作者 12. Tissue Engineering, 2006-1097:Effect of the crystalline of matrix polymer on release profiles of hemoglobin-loaded nanoparticles 通讯作者 13. Acta Biomaterialia, 2009-268:Biocompatibility and osteogenicity of degradable Ca-deficient hydroxyapatite scaffolds from calcium phosphate cement for bone tissue engineering. 通讯作者 14. Acta Biomaterialia, 2008-1873:Self-setting Bioactive Calcium-Magnesium Phosphate Cement with High Strength and Degradability for Bone Regeneration通讯作者 15. J. Endodontics, 1997-490:Evaluation of the Biocompatibility of a Nonceramic Hydroxyapatite第1作者 16. J Biomed Mater Res Part B: Appl Biomater，2009-45: One-Step Preparation of Glycopeptide Microspheres Based on α-Amino Acid-N-carboxyanhydride Polymerization using Interfacial Protocols. 通讯作者 17. J Mater Sci: Mater Med., 2009-1513: Combinatorial coating of adhesive polypeptide and anti-CD34 antibody for improved endothelial cell adhesion and proliferation 通讯作者 18. J Mater Sci: Mater Med, 2009-1025:A Noninvasive Method for Measuring the Oxygen binding-releasing Capacity of Hemoglobin-loaded Polymeric Nanoparticles Used as Oxygen Carrier. 通讯作者 19. J Mater Sci: Mater Med, 2009, DOI 10.1007/s10856-009-3746-9:In vitro macrophage uptake and in vivo biodistribution of PLA–PEG nanoparticles loaded with hemoglobin as blood substitutes: effect of PEG content通讯作者 20. J Mater Sci: Mater Med, 2009, DOI 10.1007/s10856-009-3773-6:Preparation and pharmaceutical/pharmacodynamic evaluation of topical brucine-loaded liposomal hydrogel通讯作者
21. Materials Science Forum, 2009-1364: Effect of Hydroxyapatite Nanoparticles of Different Concentrations on Rat Osteoblast通讯作者 22. J Appl Polym Sci., 2009: Preparation and Characterization of Chitosan/PEG/Gelatin Composites for Tissue Engineering 通讯作者 23. Colloids and Surface B -Biointerfaces, doi:10.1016/j.colsurfb.2009.04.017:In vitro macrophage uptake and in vivo biodistribution of long-circulation nanoparticles with poly(ethylene-glycol)-modified PLA (BAB type) triblock copolymer. 通讯作者 24. J Biomed Mater Res Part B: Appl Biomater，2008-354:Reduction and Suppression of Methemoglobin Loaded in the Polymeric Nanoparticles Intended for Blood Substitutes通讯作者 25. Materials Chemistry and Physics, 2008-275:Sol–gel auto-combustion synthesis of hydroxyapatite nanotubes array in porous alumina template通讯作者 26. Materials Chemistry and Physics, 2008-106: Preparation, mechanical properties and erosion behaviors of oriented Ca(PO3)2 glass-ceramics通讯作者 27. Materials Science and Engineering C, 2008-1572:The effect of polymeric chain-like structure on the degradation and cellular biocompatibility of calcium polyphosphate通讯作者 28. J Mater Sci: Mater Med, 2008-2463:Key parameters affecting the initial leaky effect of hemoglobin-loaded nanoparticles as blood substitutes通讯作者 29. J Mater Sci: Mater Med, 2008-2187:Plasma Deposition n- Butyl Methacrylate Coating with Potential for Stent Surface Modificatio. 通讯作者 30. Applied Surface Science，2008-270:Crystalline structure and its effects on the degradation of linear calcium polyphosphate bone substitute通讯作者 31. Materials Letters, 2008-147:Synthesis and characterization of polycationic chitosan-graft-poly (l-lysine) 通讯作者 32. J. Mater. Sci. Technol., 2008-187: Fluorescent Labeling of Nanometer Hydroxyapatite通讯作者 33. International Journal of Biological Macromolecules 2008-450:In Situ Preparation of Glycoconjugate Hollow Microspheres Mimetic the Extracellular Matrix via Interfacial Polymerization. 通讯作者 34. Biomed. Mater. (2008) doi:10.1088/1748- 35. Biomed. Mater.，2008doi:10.1088/1748- 36. Advanced Materials Research, 2008-1383:Biocompatibility and osteogenesis of calcium phosphate cement scaffolds for bone tissue engineering通讯作者 37. Research on Chemical Intermediates, 2008-169:Aggregate formation and surface activity of partially deacetylated water-soluble chitin通讯作者 38. Composites: Part B ，2007-311:Development of asymmetric gradational-changed porous chitosan membrane for guided periodontal tissue regeneration通讯作者 39. Acta Pharmacologica Sinica, 2007-1851:Preparation of Liposomal Brucine and Its Pharmaceutical/Pharmacodynamic Characterization通讯作者 40. Surface and Coatings Technology, 2007-6861: Radio Frequency Plasma Polymers of n- Butyl Methacrylate and Their Drug-Controlled Release Characteristics. I. Effect of the oxygen gas通讯作者 41. Biomed. Mater.，2007-S153Development of Calcium Silicate /Calcium Phosphate Cement for Bone Regeneration通讯作者 42. Biomed. Mater., 2007-32:Synthesis and properties of chitosan/polypeptide bioconjugate composite通讯作者 43. Journal of 44. Key Engineering Materials, 2007-823:Effects of The Composition of The Bioactive Composite Calcium Phosphate Cement on its Behavior in the Solution第1作者 45. Key Engineering Materials, 2007-2267:Research and Development of Calcium Phosphate Cement 第1作者 46. Journal of Biomedical Materials Research Part B: 47. Biomed. Mater. 2006－193：Development of a degradable cement of calcium phosphate and calcium sulfate composite for bone reconstruction通讯作者 48. Chinese Chemical Letters,2005-1641:Effect of Oxygen on Surface Properties and Drug Release Behavior of Plasma Polymer of n- Butyl Methacrylate. 通讯作者 49. J. Biomed. Mat. Res. Part B: Appl Biomater, 2004－73：The Physicochemical Properties of the Solidification of Calcium Phosphate Cement 第1作者 50. J Dalian University，2004－42:Study on the synthesis and the biological properties of nanometer hydroxyapatite第1作者 51. J. Chem. Technol. Biotechnol., 2001-1023:Determination of Membrane Area in the Ultrafiltration Process 第1作者 52. Chinese J. Traumatology, 2001-251:Pedicale Screw System Plus ACPC Perfusion to treat Fractures of Thoracolumbar Vertebrae 53. Bioceramics. 2000-853: Study on the Application of Tobramycin-loaded Calcium Phosphate Cement 通讯作者 54. Mat. Chem. Phys.,1999-78: Solution Property of Calcium phosphate Cement Hardening Body 第1作者 55. J. Am. Ceram. Soc.,1999-1052: Study on the Hydration Process of Calcium Phosphate Cement by AC Impedance Spectroscopy 第1作者 56. J. Biotech., 1998-195:Optimization of Operation Parameters in Ultrafiltration Process 第1作者 57. J. Biomed. Mat. Res.,1997－75：Mechanism of Hardening Process for a Hydroxyapatite Cement 第1作者 58. J. Mat. Sci: Mat. Med., 1997-803:Effect of Crystal Seeding on the Hydration of Calcium Phosphate Cement 第1作者 联系方式： 中国上海市200237，梅陇路130号，华东理工大学 办公室：实验15楼727室；电话：+86-21-6425-1358；传真：+86-21-6425-1358
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